Causes Of Tricuspid Regurgitation

Physiological tricuspid regurgitation is seen in up to 70 % of patients with normal tricuspid valve morphology. Pathological tricuspid regurgitation can occur due to a number of causes, a few common ones are listed –

Right heart pathology

  • Pulmonary hypertension
  • Cor pulmonale
  • Ischemic heart disease
  • Pacing lead
  • Cardiomyopathy
  • ASD/VSD – causes RV volume overload 

Valvular pathology 

  • Infective endocarditis
  • Rheumatic heart disease
  • Mitral stenosis – causing pulmonary hypertension
  • Ebstein anomaly
  • Carcinoid syndrome
  • Pathology of subvalvular apparatus
    • Rupture of chordae tendinae
    • Papillary muscle dysfunction
  • Connective tissue disease / Rheumatoid arthritis

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