The continuity equation is useful in calculating valve areas in both stenotic
and regurgitant lesions.
and regurgitant lesions.
Left ventricular contractility can be measured by calculating a change in
pressure in the ventricle during isovolumetric contraction phase (dp/dt).
Pressure half time (PHT) is the time taken for the peak early diastolic
pressure gradient to drop to half its value. It is measured in milliseconds.
It is useful in calculating the mitral valve orifice area, and is a commonly
used tool to assess severity of aortic and mitral regurgitation. It is typically
29% of the deceleration time (DT). In other words
PHT = 0.29 x DT
It has also been defined as the time interval from the maximum velocity
(Vmax) to the point where the velocity drops to Vmax / √2. This figure
should help
Pressure half-time is more useful with native valves than with prosthetic
valves, as it can overestimate the orifice area of normal functioning
prosthetic valves.
Pressure half-time is useful in calculating effective mitral valve area in
mitral stenosis
MVA = 220 / PHT
For example, if the pressure half time is 280 ms, the mitral valve area is
220 / 280 = 0.79cm2
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